Difference between revisions of "AraE"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.pdb.org/pdb/explore/explore.do?structureId=4JA4 4JA4] (the xylose transporter XylE from ''E. coli'', 39% identity, 68% similarity) {{PubMed|23624861}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96710 P96710] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P96710 P96710] | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araE_3484072_3485466_-1 araE] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araE_3484072_3485466_-1 araE] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|9401028}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9401028}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | <pubmed>9401028,9620981,,10417639,9620981 12949161, </pubmed> | + | <pubmed>9401028,9620981, 23624861,10417639,9620981 12949161, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:43, 20 August 2013
- Description: L-arabinose permease
| Gene name | araE |
| Synonyms | yvbR |
| Essential | no |
| Product | L-arabinose permease |
| Function | uptake of arabinose, galactose and xylose |
| Gene expression levels in SubtiExpress: araE | |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 50 kDa, 9.259 |
| Gene length, protein length | 1392 bp, 464 aa |
| Immediate neighbours | cggR, araR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transporters/ other, utilization of specific carbon sources, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33960
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transports arabinose, and also xylose and galactose PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: P96710
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: araE PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Esben M Quistgaard, Christian Löw, Per Moberg, Lionel Trésaugues, Pär Nordlund
Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat Struct Mol Biol: 2013, 20(6);766-8
[PubMed:23624861]
[WorldCat.org]
[DOI]
(I p)
José Manuel Inácio, Carla Costa, Isabel de Sá-Nogueira
Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 9);2345-2355
[PubMed:12949161]
[WorldCat.org]
[DOI]
(P p)
L J Mota, P Tavares, I Sá-Nogueira
Mode of action of AraR, the key regulator of L-arabinose metabolism in Bacillus subtilis.
Mol Microbiol: 1999, 33(3);476-89
[PubMed:10417639]
[WorldCat.org]
[DOI]
(P p)
O Krispin, R Allmansberger
The Bacillus subtilis AraE protein displays a broad substrate specificity for several different sugars.
J Bacteriol: 1998, 180(12);3250-2
[PubMed:9620981]
[WorldCat.org]
[DOI]
(P p)
I Sá-Nogueira, S S Ramos
Cloning, functional analysis, and transcriptional regulation of the Bacillus subtilis araE gene involved in L-arabinose utilization.
J Bacteriol: 1997, 179(24);7705-11
[PubMed:9401028]
[WorldCat.org]
[DOI]
(P p)
