Difference between revisions of "DefA"
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** [[DefA]]-[[RplV]] {{PubMed|18288106}} | ** [[DefA]]-[[RplV]] {{PubMed|18288106}} | ||
+ | ** [[Map]] competes with peptide deformylase ([[DefA]]), the first enzyme to act on nascent chains, for binding sites at the ribosomal tunnel exit {{PubMed|23770820}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
Line 135: | Line 136: | ||
=References= | =References= | ||
− | <pubmed>11429456,12627383, 18288106 16964327</pubmed> | + | <pubmed>11429456,12627383, 18288106 16964327 23770820</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 12:29, 20 August 2013
- Description: formylmethionine deformylase
Gene name | defA |
Synonyms | yloK, def |
Essential | no |
Product | formylmethionine deformylase |
Function | translation |
Gene expression levels in SubtiExpress: defA | |
MW, pI | 17 kDa, 4.731 |
Gene length, protein length | 480 bp, 160 aa |
Immediate neighbours | priA, fmt |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
translation, protein modification
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15720
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Formyl-L-methionyl peptide + H2O = formate + methionyl peptide (according to Swiss-Prot)
- Protein family: polypeptide deformylase family (according to Swiss-Prot)
- Paralogous protein(s): DefB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P94462
- KEGG entry: [2]
- E.C. number: 3.5.1.88
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References