Difference between revisions of "DefA"

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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 
** [[DefA]]-[[RplV]] {{PubMed|18288106}}  
 
** [[DefA]]-[[RplV]] {{PubMed|18288106}}  
 +
** [[Map]] competes with peptide deformylase ([[DefA]]), the first enzyme to act on nascent chains, for binding sites at the ribosomal tunnel exit {{PubMed|23770820}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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=References=
 
=References=
<pubmed>11429456,12627383, 18288106 16964327</pubmed>
+
<pubmed>11429456,12627383, 18288106 16964327 23770820</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:29, 20 August 2013

  • Description: formylmethionine deformylase

Gene name defA
Synonyms yloK, def
Essential no
Product formylmethionine deformylase
Function translation
Gene expression levels in SubtiExpress: defA
MW, pI 17 kDa, 4.731
Gene length, protein length 480 bp, 160 aa
Immediate neighbours priA, fmt
Sequences Protein DNA DNA_with_flanks
Genetic context
Def context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Def expression.png















Categories containing this gene/protein

translation, protein modification

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Formyl-L-methionyl peptide + H2O = formate + methionyl peptide (according to Swiss-Prot)
  • Protein family: polypeptide deformylase family (according to Swiss-Prot)
  • Paralogous protein(s): DefB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References