Difference between revisions of "Tig"
| Line 15: | Line 15: | ||
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28230 tig] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28230 tig] | ||
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Tig Tig] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 4.224 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 4.224 | ||
| Line 35: | Line 37: | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
| − | |||
| − | |||
| − | |||
| − | |||
<br/><br/> | <br/><br/> | ||
| Line 92: | Line 90: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[Tig]]-[[RplW]] {{PubMed|16271892,16091460}} | ||
| + | ** [[Tig]]-[[RpmC]] {{PubMed|16271892,16091460}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| Line 147: | Line 147: | ||
<pubmed>16231086 15763705 15837180 19647435 </pubmed> | <pubmed>16231086 15763705 15837180 19647435 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>12224648,9748346,9063446,18497744 ,16493705, 8969504 20525796 22517742</pubmed> | + | <pubmed>12224648,9748346,9063446,18497744 ,16493705, 8969504 20525796 22517742 16271892,16091460</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:10, 20 August 2013
- Description: trigger factor (prolyl isomerase)
| Gene name | tig |
| Synonyms | yzzH |
| Essential | no |
| Product | trigger factor (prolyl isomerase) |
| Function | protein folding |
| Gene expression levels in SubtiExpress: tig | |
| Interactions involving this protein in SubtInteract: Tig | |
| MW, pI | 47 kDa, 4.224 |
| Gene length, protein length | 1272 bp, 424 aa |
| Immediate neighbours | clpX, ysoA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
chaperones/ protein folding, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: Tig subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P80698
- KEGG entry: [3]
- E.C. number:
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon: tig PubMed
- Sigma factor:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Carmela Giglione, Sonia Fieulaine, Thierry Meinnel
Cotranslational processing mechanisms: towards a dynamic 3D model.
Trends Biochem Sci: 2009, 34(8);417-26
[PubMed:19647435]
[WorldCat.org]
[DOI]
(I p)
R D Wegrzyn, E Deuerling
Molecular guardians for newborn proteins: ribosome-associated chaperones and their role in protein folding.
Cell Mol Life Sci: 2005, 62(23);2727-38
[PubMed:16231086]
[WorldCat.org]
[DOI]
(P p)
Timm Maier, Lars Ferbitz, Elke Deuerling, Nenad Ban
A cradle for new proteins: trigger factor at the ribosome.
Curr Opin Struct Biol: 2005, 15(2);204-12
[PubMed:15837180]
[WorldCat.org]
[DOI]
(P p)
Elke Deuerling, Bernd Bukau
Chaperone-assisted folding of newly synthesized proteins in the cytosol.
Crit Rev Biochem Mol Biol: 2004, 39(5-6);261-77
[PubMed:15763705]
[WorldCat.org]
[DOI]
(P p)
Original publications
