Difference between revisions of "DefA"

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m (Jstuelk moved page Def to DefA: 23944997)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''def''
+
|''defA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yloK ''
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yloK, def ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
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|style="background:#ABCDEF;" align="center"| '''Product''' || formylmethionine deformylase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || formylmethionine deformylase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || translation  
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[translation]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15720 def]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15720 defA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.731   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.731   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[def]]-[[fmt]]-[[yloM]]'' [http://www.ncbi.nlm.nih.gov/pubmed/16964327?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PubMed]
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* '''Operon:''' ''[[defA]]-[[fmt]]-[[yloM]]'' {{PubMed|16964327}}
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=defA_1646512_1646994_1 def] {{PubMed|22383849}}
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=defA_1646512_1646994_1 defA] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16964327?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PubMed]
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* '''[[Sigma factor]]:''' [[SigA]] ''[[defA]]-[[fmt]]-[[yloM]]'' {{PubMed|16964327}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 10:58, 18 August 2013

  • Description: formylmethionine deformylase

Gene name defA
Synonyms yloK, def
Essential no
Product formylmethionine deformylase
Function translation
Gene expression levels in SubtiExpress: defA
MW, pI 17 kDa, 4.731
Gene length, protein length 480 bp, 160 aa
Immediate neighbours priA, fmt
Sequences Protein DNA DNA_with_flanks
Genetic context
Def context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Def expression.png















Categories containing this gene/protein

translation, protein modification

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Formyl-L-methionyl peptide + H2O = formate + methionyl peptide (according to Swiss-Prot)
  • Protein family: polypeptide deformylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Julia Elisabeth Bandow, Dörte Becher, Knut Büttner, Falko Hochgräfe, Christoph Freiberg, Heike Brötz, Michael Hecker
The role of peptide deformylase in protein biosynthesis: a proteomic study.
Proteomics: 2003, 3(3);299-306
[PubMed:12627383] [WorldCat.org] [DOI] (P p)

Michael Haas, Dieter Beyer, Reinhold Gahlmann, Christoph Freiberg
YkrB is the main peptide deformylase in Bacillus subtilis, a eubacterium containing two functional peptide deformylases.
Microbiology (Reading): 2001, 147(Pt 7);1783-1791
[PubMed:11429456] [WorldCat.org] [DOI] (P p)