Difference between revisions of "CotG"
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| − | * '''Description:''' spore coat protein <br/><br/> | + | * '''Description:''' outer spore coat protein <br/><br/> |
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{{SubtiWiki regulon|[[GerE regulon]]}}, | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
{{SubtiWiki regulon|[[GerR regulon]]}}, | {{SubtiWiki regulon|[[GerR regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigE regulon]]}}, | ||
{{SubtiWiki regulon|[[SigK regulon]]}} | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
| Line 96: | Line 93: | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** outer spore coat, localization depends on [[CotE]] {{PubMed|22171814}} | ||
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotG_3717238_3717825_1 cotG] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotG_3717238_3717825_1 cotG] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigK]] {{PubMed|15699190,7814326}} | + | * '''Sigma factor:''' [[SigE]] {{PubMed|15383836}}, [[SigK]] {{PubMed|15699190,7814326}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,7814326}} | + | ** expressed late during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]]) {{PubMed|15383836,15699190,7814326}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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=References= | =References= | ||
| − | + | <pubmed>12884008,7814326,9573176,14762006, 15699190 15621419 22171814 21984783 15383836</pubmed> | |
| − | <pubmed>12884008,7814326,9573176,14762006, 15699190 15621419 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:31, 13 August 2013
- Description: outer spore coat protein
| Gene name | cotG |
| Synonyms | |
| Essential | no |
| Product | spore coat protein |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotG | |
| Interactions involving this protein in SubtInteract: CotG | |
| MW, pI | 23 kDa, 10.673 |
| Gene length, protein length | 585 bp, 195 aa |
| Immediate neighbours | cotH, ywrF |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
GerE regulon, GerR regulon, SigE regulon, SigK regulon
The gene
Basic information
- Locus tag: BSU36070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39801
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Rosa Giglio, Renato Fani, Rachele Isticato, Maurilio De Felice, Ezio Ricca, Loredana Baccigalupi
Organization and evolution of the cotG and cotH genes of Bacillus subtilis.
J Bacteriol: 2011, 193(23);6664-73
[PubMed:21984783]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Ritsuko Kuwana, Takashi Okumura, Hiromu Takamatsu, Kazuhito Watabe
The ylbO gene product of Bacillus subtilis is involved in the coat development and lysozyme resistance of spore.
FEMS Microbiol Lett: 2005, 242(1);51-7
[PubMed:15621419]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
Rita Zilhão, Mónica Serrano, Rachele Isticato, Ezio Ricca, Charles P Moran, Adriano O Henriques
Interactions among CotB, CotG, and CotH during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2004, 186(4);1110-9
[PubMed:14762006]
[WorldCat.org]
[DOI]
(P p)
G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008]
[WorldCat.org]
[DOI]
(P p)
A O Henriques, L R Melsen, C P Moran
Involvement of superoxide dismutase in spore coat assembly in Bacillus subtilis.
J Bacteriol: 1998, 180(9);2285-91
[PubMed:9573176]
[WorldCat.org]
[DOI]
(P p)
M Sacco, E Ricca, R Losick, S Cutting
An additional GerE-controlled gene encoding an abundant spore coat protein from Bacillus subtilis.
J Bacteriol: 1995, 177(2);372-7
[PubMed:7814326]
[WorldCat.org]
[DOI]
(P p)
