Difference between revisions of "DgrA"
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| − | * '''Description:''' c-di-GMP receptor protein, inhibits motility | + | * '''Description:''' c-di-GMP receptor protein, inhibits motility at high c-di-GMP concentrations<br/><br/> |
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| + | ** K(D) for c-di-GMP: 1.1 nM {{PubMed|23893111}} | ||
* '''Domains:''' | * '''Domains:''' | ||
Revision as of 11:12, 10 August 2013
- Description: c-di-GMP receptor protein, inhibits motility at high c-di-GMP concentrations
| Gene name | dgrA |
| Synonyms | ypfA, jofA |
| Essential | no |
| Product | c-di-GMP receptor protein |
| Function | control of MotA activity |
| Gene expression levels in SubtiExpress: DgrA | |
| Interactions involving this protein in SubtInteract: DgrA | |
| MW, pI | 24 kDa, 7.878 |
| Gene length, protein length | 651 bp, 217 aa |
| Immediate neighbours | ypfB, ypeB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22910
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- K(D) for c-di-GMP: 1.1 nM PubMed
- Domains:
- contains a C-terminal PilZ domain PubMed
- Modification:
- Cofactor(s):
- c-di-GMP PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P38491
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Xiaohui Gao, Sampriti Mukherjee, Paige M Matthews, Loubna A Hammad, Daniel B Kearns, Charles E Dann
Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway.
J Bacteriol: 2013, 195(21);4782-92
[PubMed:23893111]
[WorldCat.org]
[DOI]
(I p)
Yun Chen, Yunrong Chai, Jian-hua Guo, Richard Losick
Evidence for cyclic Di-GMP-mediated signaling in Bacillus subtilis.
J Bacteriol: 2012, 194(18);5080-90
[PubMed:22821967]
[WorldCat.org]
[DOI]
(I p)
