Difference between revisions of "SftA"

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=References=
 
=References=
 
==Reviews==
 
==Reviews==
<pubmed> 22047950 </pubmed>
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<pubmed> 22047950 22934648 </pubmed>
 +
 
 
==Original publications==
 
==Original publications==
 
<pubmed>16479537 19788545 19818024 21239579</pubmed>
 
<pubmed>16479537 19788545 19818024 21239579</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:07, 29 July 2013

  • Description: DNA translocase

Gene name sftA
Synonyms ytpS, cdtA
Essential no
Product DNA translocase
Function resolution of chromosome dimers
Gene expression levels in SubtiExpress: sftA
MW, pI 107 kDa, 5.052
Gene length, protein length 2856 bp, 952 aa
Immediate neighbours murC, ytpR
Sequences Protein DNA DNA_with_flanks
Genetic context
YtpS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SftA expression.png
























Categories containing this gene/protein

DNA condensation/ segregation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29805

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
    • the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Rodrigo Reyes-Lamothe, Emilien Nicolas, David J Sherratt
Chromosome replication and segregation in bacteria.
Annu Rev Genet: 2012, 46;121-43
[PubMed:22934648] [WorldCat.org] [DOI] (I p)

Christine Kaimer, Peter L Graumann
Players between the worlds: multifunctional DNA translocases.
Curr Opin Microbiol: 2011, 14(6);719-25
[PubMed:22047950] [WorldCat.org] [DOI] (I p)


Original publications