Difference between revisions of "IspG"
| Line 95: | Line 95: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=3NOY 3NOY] (from ''Aquifex aeolicus'', 51% identity) {{PubMed|20932974}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P54482 P54482] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P54482 P54482] | ||
| Line 139: | Line 139: | ||
=References= | =References= | ||
| − | <pubmed>12662922 15383836 17458547 23832336 23840410 </pubmed> | + | <pubmed>12662922 15383836 17458547 23832336 23840410 20932974 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:58, 12 July 2013
- Description: similar to peptidoglycan acetylation, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate synthase, 6th step in the MEP pathway of isoprenoid biosynthesis
| Gene name | ispG |
| Synonyms | yqfY |
| Essential | yes PubMed |
| Product | 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate synthase |
| Function | MEP pathway of isoprenoid biosynthesis |
| Gene expression levels in SubtiExpress: ispG | |
| MW, pI | 40 kDa, 6.802 |
| Gene length, protein length | 1131 bp, 377 aa |
| Immediate neighbours | yqfZ, yqfX |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, sporulation proteins, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25070
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + protein-disulfide = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein-dithiol (according to Swiss-Prot)
- Protein family: ispG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): contains an iron-sulfur cluster
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- UniProt: P54482
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
