Difference between revisions of "Epr"
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{{SubtiWiki regulon|[[ScoC regulon]]}}, | {{SubtiWiki regulon|[[ScoC regulon]]}}, | ||
{{SubtiWiki regulon|[[SigD regulon]]}}, | {{SubtiWiki regulon|[[SigD regulon]]}}, | ||
| − | {{SubtiWiki regulon|[[SinR regulon]]}} | + | {{SubtiWiki regulon|[[SinR regulon]]}}, |
| + | {{SubtiWiki regulon|[[Spo0A regulon]]}} | ||
=The gene= | =The gene= | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | * '''[[Localization]]:''' | + | * '''[[Localization]]:''' |
| + | ** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] | ||
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=epr_3939869_3941806_1 epr] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=epr_3939869_3941806_1 epr] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigD]] {{PubMed|11751842}} | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|11751842}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by [[SinR]] | + | ** repressed by [[SinR]] {{PubMed|16923912}} |
| − | ** repressed during exponential growth ([[ScoC]]) | + | ** repressed during exponential growth ([[ScoC]]) {{PubMed|16923912}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** activation by [[DegU]], not activated by [[DegU]]-P {{PubMed|19416356}} | ** activation by [[DegU]], not activated by [[DegU]]-P {{PubMed|19416356}} | ||
| − | ** [[SinR]]: transcription repression | + | ** [[SinR]]: transcription repression{{PubMed|16923912}} |
| − | ** [[ScoC]]: transcription repression [ | + | ** [[ScoC]]: transcription repression {{PubMed|16923912}} |
| + | ** [[Spo0A]]: prevents repression by [[SinR]] {{PubMed|23660663}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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<pubmed>20735481 </pubmed> | <pubmed>20735481 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>16923912,3142851 19416356 , 18957862, 19416356 11751842 </pubmed> | + | <pubmed>16923912,3142851 19416356 , 18957862, 19416356 11751842 23660663 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:05, 24 May 2013
- Description: minor extracellular serine protease, involved in control of swarming motility PubMed
| Gene name | epr |
| Synonyms | ipa-15r |
| Essential | no |
| Product | minor extracellular serine protease |
| Function | protein degradation |
| Gene expression levels in SubtiExpress: epr | |
| MW, pI | 69 kDa, 9.875 |
| Gene length, protein length | 1935 bp, 645 aa |
| Immediate neighbours | ywbA, sacX |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of nitrogen sources other than amino acids, proteolysis, motility and chemotaxis
This gene is a member of the following regulons
DegU regulon, ScoC regulon, SigD regulon, SinR regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU38400
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S8 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
Database entries
- Structure:
- UniProt: P16396
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Original publications
