Difference between revisions of "Zwf"
Line 31: | Line 31: | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
− | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=zwf_2479156_2480625_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:zwf_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=zwf_2479156_2480625_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:zwf_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23850]] |
|- | |- | ||
|} | |} |
Revision as of 13:50, 16 May 2013
- Description: glucose 6-phosphate dehydrogenase, pentose-phosphate pathway
Gene name | zwf |
Synonyms | yqjJ |
Essential | no |
Product | glucose 6-phosphate dehydrogenase |
Function | initiation of the pentose phosphate pathway |
Gene expression levels in SubtiExpress: zwf | |
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
MW, pI | 55 kDa, 5.28 |
Gene length, protein length | 1467 bp, 489 aa |
Immediate neighbours | rnz, gndA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23850
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH (according to Swiss-Prot)
- Protein family: glucose-6-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information: Two Substrate Michaelis-Menten PubMed
- Domains:
- Modification:
- Cofactor(s): Mg2+, Mn2+, Ca2+
- Effectors of protein activity:
- NAD+, NADP+ and NADPH affect the enzyme kinetic PubMed
- Interactions:
- Localization:
Database entries
- UniProt: P54547
- KEGG entry: [3]
- E.C. number: 1.1.1.49
Additional information
The enzyme is a dimer PubMed
Expression and regulation
- Operon: zwf PubMed
- Sigma factor:
- Regulation: constitutive PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- SM-NB3 (zwf-spc), available in Anne Galinier's and Boris Görke's labs
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References