DacC

• Description: penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
  
  

Gene name	dacC
Synonyms	pbp
Essential	no
Product	penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
Function	carboxypeptidase
Gene expression levels in SubtiExpress: dacC
MW, pI	52 kDa, 5.413
Gene length, protein length	1473 bp, 491 aa
Immediate neighbours	ppsA, galM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

• Locus tag: BSU18350

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

• A mutation was found in this gene after evolution under relexed selection for sporulation PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • may be part of the cell wall biosynthetic complex PubMed

• Localization:

Database entries

• Structure: 1W5D, 2J9P (complex with a peptidoglycan mimetic peptide)

• UniProt: P39844

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: galM-dacC PubMed

• Expression browser: dacC PubMed

• Sigma factor: SigH PubMed, SigB PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: