SodF

• Description: superoxide dismutase
  
  

Gene name	sodF
Synonyms
Essential	no
Product	superoxide dismutase
Function	detoxification of oxygen radicals
Gene expression levels in SubtiExpress: sodF
MW, pI	33 kDa, 6.17
Gene length, protein length	843 bp, 281 aa
Immediate neighbours	sqhC, yocR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU19330

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 superoxide + 2 H⁺ = O₂ + H₂O₂ (according to Swiss-Prot)

• Protein family: terpene cyclase/mutase family (according to Swiss-Prot)

• Paralogous protein(s): SodA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O35023

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: sqhC-sodF PubMed

• Expression browser: sodF PubMed

• Sigma factor: SigE PubMed

• Regulation: expressed during sporulation in the mother cell PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

T Bosak, R M Losick, A Pearson
A polycyclic terpenoid that alleviates oxidative stress.
Proc Natl Acad Sci U S A: 2008, 105(18);6725-9
[PubMed:18436644] [WorldCat.org] [DOI] (I p)