YkfA

• Description: similar to immunity to bacteriotoxins
  
  

Gene name	ykfA
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ykfA
MW, pI	25 kDa, 5.409
Gene length, protein length	702 bp, 234 aa
Immediate neighbours	dppE, ykfB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

• Locus tag: BSU12970

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase S66 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34851

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ykfA PubMed

• Sigma factor:

• Regulation: repressed by CodY PubMed

• Regulatory mechanism: CodY: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)