ConE

Gene name	conE
Synonyms	yddE
Essential	no
Product	conjugation protein
Function	conjugative transfer of ICEBs1
Gene expression levels in SubtiExpress: conE
MW, pI	96 kDa, 5.511
Gene length, protein length	2493 bp, 831 aa
Immediate neighbours	yddD, yddF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

mobile genetic elements

The gene

Basic information

• Locus tag: BSU04940

Phenotypes of a mutant

Defective for conjugal transfer of ICEBs1

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: required for conjugative transfer of ICEBs1, putative ATPase PubMed

• Protein family: HerA/FtsK Superfamily of ATPases including the well-studied proteins FtsK, SpoIIIE, VirB4, and VirD4

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • Located at the cell poles, in close association with the membrane

Database entries

• Structure:

• UniProt: P96642

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: conE PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Melanie Barker Berkmen, Suffolk University, Boston, MA Homepage

References

Melanie B Berkmen, Catherine A Lee, Emma-Kate Loveday, Alan D Grossman
Polar positioning of a conjugation protein from the integrative and conjugative element ICEBs1 of Bacillus subtilis.
J Bacteriol: 2010, 192(1);38-45
[PubMed:19734305] [WorldCat.org] [DOI] (I p)