YclJ

• Description: two-component response regulator, active under anaerobic conditions
  
  

Gene name	yclJ
Synonyms
Essential	no
Product	two-component response regulator
Function	unknown
Gene expression levels in SubtiExpress: yclJ
Interactions involving this protein in SubtInteract: YclJ
MW, pI	26 kDa, 4.58
Gene length, protein length	681 bp, 227 aa
Immediate neighbours	yclI, yclK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

ResD regulon

The gene

Basic information

• Locus tag: BSU03750

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family of two-component response regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by YclK on an Asp residue

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions:
  • YclK-YclJ (putative)

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94413

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yclJ-yclK PubMed

• Expression browser: yclJ PubMed

• Sigma factor:

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Elisabeth Härtig, Hao Geng, Anja Hartmann, Angela Hubacek, Richard Münch, Rick W Ye, Dieter Jahn, Michiko M Nakano
Bacillus subtilis ResD induces expression of the potential regulatory genes yclJK upon oxygen limitation.
J Bacteriol: 2004, 186(19);6477-84
[PubMed:15375128] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)