Difference between revisions of "PhrG"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40310 phrG] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PhrG PhrG] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PhrG PhrG] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rapG]]'', ''[[rocF]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rapG]]'', ''[[rocF]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40310 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40310 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40310 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:phrG_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:phrG_context.gif]] | ||
Revision as of 14:18, 13 May 2013
- Description: response regulator aspartate phosphatase (RapG) regulator
| Gene name | phrG |
| Synonyms | yycL |
| Essential | no |
| Product | phosphatase (RapG) regulator |
| Function | control of DegU activity |
| Gene expression levels in SubtiExpress: phrG | |
| Interactions involving this protein in SubtInteract: PhrG | |
| MW, pI | 4 kDa, 9.017 |
| Gene length, protein length | 114 bp, 38 aa |
| Immediate neighbours | rapG, rocF |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control, quorum sensing, short peptides
This gene is a member of the following regulons
CcpA regulon, RghR regulon, SigH regulon
The gene
Basic information
- Locus tag: BSU40310
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to RapG, this results in the inability of RapG to interact with DegU PubMed
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32295
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kentaro Hayashi, Tsukahara Kensuke, Kazuo Kobayashi, Naotake Ogasawara, Mitsuo Ogura
Bacillus subtilis RghR (YvaN) represses rapG and rapH, which encode inhibitors of expression of the srfA operon.
Mol Microbiol: 2006, 59(6);1714-29
[PubMed:16553878]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Kana Shimane, Kei Asai, Naotake Ogasawara, Teruo Tanaka
Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1685-97
[PubMed:12950930]
[WorldCat.org]
[DOI]
(P p)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
