Difference between revisions of "HutI"
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|style="background:#ABCDEF;" align="center"|'''Function''' || histidine utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || histidine utilization | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39370 hutI] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hutU]]'', ''[[hutG]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hutU]]'', ''[[hutG]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39370 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39370 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39370 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:hutI_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:hutI_context.gif]] | ||
Revision as of 14:14, 13 May 2013
- Description: imidazolone-5-propionate hydrolase
| Gene name | hutI |
| Synonyms | |
| Essential | no |
| Product | imidazolone-5-propionate hydrolase |
| Function | histidine utilization |
| Gene expression levels in SubtiExpress: hutI | |
| Metabolic function and regulation of this protein in SubtiPathways: His | |
| MW, pI | 45 kDa, 5.215 |
| Gene length, protein length | 1263 bp, 421 aa |
| Immediate neighbours | hutU, hutG |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
CcpA regulon, CodY regulon, HutP regulon
The gene
Basic information
- Locus tag: BSU39370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H2O = N-formimidoyl-L-glutamate + H+ (according to Swiss-Prot)
- Protein family: hutI family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2BB0
- UniProt: P42084
- KEGG entry: [3]
- E.C. number: 3.5.2.7
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Robert A Bender
Regulation of the histidine utilization (hut) system in bacteria.
Microbiol Mol Biol Rev: 2012, 76(3);565-84
[PubMed:22933560]
[WorldCat.org]
[DOI]
(I p)
Original publications
