Difference between revisions of "MinD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || septum placement
 
|style="background:#ABCDEF;" align="center"|'''Function''' || septum placement
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27990 minD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27990 minD]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/MinD MinD]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/MinD MinD]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVFA]]'', ''[[minC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVFA]]'', ''[[minC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14759&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27990 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27990 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27990 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:minD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:minD_context.gif]]

Revision as of 13:28, 13 May 2013

  • Description: cell-division inhibitor (septum placement), part of the Min system (with DivIVA, MinC, MinJ), Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring placement

Gene name minD
Synonyms divIVB1
Essential no
Product cell-division inhibitor
Function septum placement
Gene expression levels in SubtiExpress: minD
Interactions involving this protein in SubtInteract: MinD
MW, pI 29 kDa, 4.984
Gene length, protein length 804 bp, 268 aa
Immediate neighbours spoIVFA, minC
Sequences Protein DNA Advanced_DNA
Genetic context
MinD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MinD expression.png
























Categories containing this gene/protein

cell division, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigH regulon, SigM regulon

The gene

Basic information

  • Locus tag: BSU27990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle PubMed
  • Protein family: MinD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • polar/ septal at the cell membrane PubMed
    • membrane binding/ polar localization depends on the proton motive force PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications

Additional publications: PubMed