Difference between revisions of "GreA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || transcription elongation | |style="background:#ABCDEF;" align="center"|'''Function''' || transcription elongation | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27320 greA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.475 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.475 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pbpI]]'', ''[[udk]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pbpI]]'', ''[[udk]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27320 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:greA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:greA_context.gif]] | ||
Revision as of 13:26, 13 May 2013
- Description: transcription elongation factor, resolves stalled RNA polymerase at promoter or promoter-proximal regions,
| Gene name | greA |
| Synonyms | |
| Essential | no |
| Product | transcription elongation factor |
| Function | transcription elongation |
| Gene expression levels in SubtiExpress: greA | |
| MW, pI | 17 kDa, 4.475 |
| Gene length, protein length | 471 bp, 157 aa |
| Immediate neighbours | pbpI, udk |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27320
Phenotypes of a mutant
- RNA polymerase accumulates in promoter-proximal regions of many genes PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: greA/greB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: uniformly distributed throughout the nucleoid PubMed
Database entries
- Structure:
- UniProt: P80240
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Alžbeta Rabatinová, Hana Šanderová, Jitka Jirát Matějčková, Jana Korelusová, Luděk Sojka, Ivan Barvík, Veronika Papoušková, Vladimír Sklenár, Lukáš Žídek, Libor Krásný
The δ subunit of RNA polymerase is required for rapid changes in gene expression and competitive fitness of the cell.
J Bacteriol: 2013, 195(11);2603-11
[PubMed:23543716]
[WorldCat.org]
[DOI]
(I p)
Yoko Kusuya, Ken Kurokawa, Shu Ishikawa, Naotake Ogasawara, Taku Oshima
Transcription factor GreA contributes to resolving promoter-proximal pausing of RNA polymerase in Bacillus subtilis cells.
J Bacteriol: 2011, 193(12);3090-9
[PubMed:21515770]
[WorldCat.org]
[DOI]
(I p)
Mohammad Roghanian, Yulia Yuzenkova, Nikolay Zenkin
Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre.
Nucleic Acids Res: 2011, 39(10);4352-9
[PubMed:21266474]
[WorldCat.org]
[DOI]
(I p)
Geoff P Doherty, Donna H Meredith, Peter J Lewis
Subcellular partitioning of transcription factors in Bacillus subtilis.
J Bacteriol: 2006, 188(11);4101-10
[PubMed:16707701]
[WorldCat.org]
[DOI]
(P p)
