Difference between revisions of "YqiQ"

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|style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism
 
|style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24120 yqiQ]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24120 yqiQ]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html Coenzyme A], [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html Coenzyme A], [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqzF]]'', ''[[mmgE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqzF]]'', ''[[mmgE]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14343&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24120 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24120 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24120 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yqiQ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqiQ_context.gif]]

Revision as of 13:14, 13 May 2013

  • Description: methylisocitrate lyase

Gene name yqiQ
Synonyms prpB
Essential no
Product methylisocitrate lyase
Function mother cell metabolism
Gene expression levels in SubtiExpress: yqiQ
Metabolic function and regulation of this protein in SubtiPathways:
Coenzyme A, Central C-metabolism
MW, pI 32 kDa, 5.279
Gene length, protein length 903 bp, 301 aa
Immediate neighbours yqzF, mmgE
Sequences Protein DNA Advanced_DNA
Genetic context
YqiQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqiQ expression.png




























Categories containing this gene/protein

sporulation proteins, membrane proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

CcpA regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU24120

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate (according to Swiss-Prot)
  • Protein family: Methylisocitrate lyase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1MUM (enzyme of E. coli), 3KZ2 (the enzyme from B. anthracis)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
    • repressed by glucose (CcpA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References