Difference between revisions of "KamA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU19690 kamA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19690 kamA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 6.04   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 6.04   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yokU]]'', ''[[yodP]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yokU]]'', ''[[yodP]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13860&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19690 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19690 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19690 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:kamA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:kamA_context.gif]]

Revision as of 13:01, 13 May 2013

  • Description: lysine 2,3-aminomutase

Gene name kamA
Synonyms yodO
Essential no
Product lysine 2,3-aminomutase
Function unknown
Gene expression levels in SubtiExpress: kamA
MW, pI 53 kDa, 6.04
Gene length, protein length 1413 bp, 471 aa
Immediate neighbours yokU, yodP
Sequences Protein DNA Advanced_DNA
Genetic context
KamA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
KamA expression.png

























Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon


The gene

Basic information

  • Locus tag: BSU19690

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-lysine = beta-lysine
  • Protein family: UPF0720 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: expressed early during sporuation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)