Difference between revisions of "YodB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of quinone and diamide detoxification | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of quinone and diamide detoxification | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19540 yodB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 4.737 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 4.737 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yodA]]'', ''[[yodC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yodA]]'', ''[[yodC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19540 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yodB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yodB_context.gif]] | ||
Revision as of 13:01, 13 May 2013
- Description: MarR/DUF24 family transcription repressor of azoR1, catD-catE and yodC expression
| Gene name | yodB |
| Synonyms | |
| Essential | no |
| Product | MarR/DUF24 family transcription repressor |
| Function | regulation of quinone and diamide detoxification |
| Gene expression levels in SubtiExpress: yodB | |
| MW, pI | 12 kDa, 4.737 |
| Gene length, protein length | 336 bp, 112 aa |
| Immediate neighbours | yodA, yodC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The YodB regulon:
The gene
Basic information
- Locus tag: BSU19540
Phenotypes of a mutant
- increased resistance to catechol, quinones and diamide PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: MarR/DUF24 family
- Paralogous protein(s): CatR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: redox-controlled by intersubunit disulfide formation of Cys6 and Cys101' in response to quinones and diamide
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34844
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- subject to autorepression PubMed
- Regulatory mechanism:
- YodB: transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Haike Antelmann,University of Greifswald, Germany
Your additional remarks
References
Reviews
Antelmann H, Helmann JD. Thiol-based redox switches and gene regulation. Antioxid Redox Signal. 2011,14:1049-63. PubMed
Original Publications
