Difference between revisions of "PenP"
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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to beta-lactam antibiotics | |style="background:#ABCDEF;" align="center"|'''Function''' || resistance to beta-lactam antibiotics | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18800 penP] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 9.208 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 9.208 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoaZ]]'', ''[[yobA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoaZ]]'', ''[[yobA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18800 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18800 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18800 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:penP_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:penP_context.gif]] | ||
Revision as of 12:59, 13 May 2013
- Description: beta-lactamase
| Gene name | penP |
| Synonyms | |
| Essential | no |
| Product | beta-lactamase |
| Function | resistance to beta-lactam antibiotics |
| Gene expression levels in SubtiExpress: penP | |
| MW, pI | 33 kDa, 9.208 |
| Gene length, protein length | 918 bp, 306 aa |
| Immediate neighbours | yoaZ, yobA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
resistance against toxins/ antibiotics
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU18800
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A beta-lactam + H2O = a substituted beta-amino acid (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
Database entries
- Structure: 3KGM (from B. licheniformis, 58% identity, 79% similarity)
- UniProt: P39824
- KEGG entry: [2]
- E.C. number: 3.5.2.6
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
