Difference between revisions of "CtaB"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14880 ctaB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 9.566 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 9.566 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ctaA]]'', ''[[ctaC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ctaA]]'', ''[[ctaC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14880 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14880 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14880 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ctaB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ctaB_context.gif]] | ||
Revision as of 12:44, 13 May 2013
- Description: heme O synthase (major enzyme)
| Gene name | ctaB |
| Synonyms | |
| Essential | no |
| Product | heme O synthase (major enzyme) |
| Function | heme biosynthesis |
| Gene expression levels in SubtiExpress: ctaB | |
| MW, pI | 33 kDa, 9.566 |
| Gene length, protein length | 915 bp, 305 aa |
| Immediate neighbours | ctaA, ctaC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14880
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ubiA prenyltransferase family, Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)
- Paralogous protein(s): CtaO
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P24009
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Tatsushi Mogi
Over-expression and characterization of Bacillus subtilis heme O synthase.
J Biochem: 2009, 145(5);669-75
[PubMed:19204012]
[WorldCat.org]
[DOI]
(I p)
Brienne M Brown, Zhihong Wang, Kenneth R Brown, Julia A Cricco, Eric L Hegg
Heme O synthase and heme A synthase from Bacillus subtilis and Rhodobacter sphaeroides interact in Escherichia coli.
Biochemistry: 2004, 43(42);13541-8
[PubMed:15491161]
[WorldCat.org]
[DOI]
(P p)
X Liu, H W Taber
Catabolite regulation of the Bacillus subtilis ctaBCDEF gene cluster.
J Bacteriol: 1998, 180(23);6154-63
[PubMed:9829923]
[WorldCat.org]
[DOI]
(P p)
B Svensson, M Lübben, L Hederstedt
Bacillus subtilis CtaA and CtaB function in haem A biosynthesis.
Mol Microbiol: 1993, 10(1);193-201
[PubMed:7968515]
[WorldCat.org]
[DOI]
(P p)
