YfmC

• Description: iron/ citrate ABC transporter (binding protein)
  
  

Gene name	yfmC
Synonyms
Essential	no
Product	iron/ citrate ABC transporter (binding protein)
Function	iron uptake
Gene expression levels in SubtiExpress: yfmC
Interactions involving this protein in SubtInteract: YfmC
MW, pI	34 kDa, 7.879
Gene length, protein length	945 bp, 315 aa
Immediate neighbours	yfmD, yfmB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07520

Phenotypes of a mutant

• poor growth with the Fe(III)-dicitrate as single source of iron PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Fe/B12 periplasmic-binding domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YfmF-(YfmD-YfmE)-(YfmC-YhfQ) PubMed

• Localization:
  • associated to the membrane (via YfmD-YfmE) PubMed
  • extracellular (signal peptide) PubMed, lipid modification as retention signal

Database entries

• Structure:

• UniProt: O34348

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yfmC-yfmD-yfmE-yfmF PubMed

• Expression browser: yfmC PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: