Difference between revisions of "TmrB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to tunicamycin | |style="background:#ABCDEF;" align="center"|'''Function''' || resistance to tunicamycin | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03140 tmrB] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 9.714 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 9.714 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nadE]]'', ''[[aroK]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nadE]]'', ''[[aroK]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03140 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03140 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03140 Advanced_DNA] |
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Revision as of 12:06, 13 May 2013
- Description: tunicamycin resistance protein, ATP-binding membrane protein
| Gene name | tmrB |
| Synonyms | |
| Essential | no |
| Product | tunicamycin resistance protein |
| Function | resistance to tunicamycin |
| Gene expression levels in SubtiExpress: tmrB | |
| MW, pI | 22 kDa, 9.714 |
| Gene length, protein length | 591 bp, 197 aa |
| Immediate neighbours | nadE, aroK |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
resistance against toxins/ antibiotics, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03140
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P12921
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: tmrB (according to DBTBS)
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Y Noda, K Yoda, A Takatsuki, M Yamasaki
TmrB protein, responsible for tunicamycin resistance of Bacillus subtilis, is a novel ATP-binding membrane protein.
J Bacteriol: 1992, 174(13);4302-7
[PubMed:1624425]
[WorldCat.org]
[DOI]
(P p)
