Difference between revisions of "CypC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of beta-hydroxy fatty acid for lipopeptides
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of beta-hydroxy fatty acid for lipopeptides
 
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|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02100 cypC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02100 cypC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 6.468   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 6.468   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxI]]'', ''[[ybyB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxI]]'', ''[[ybyB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12004&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02100 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:cypC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:cypC_context.gif]]

Revision as of 12:01, 13 May 2013

  • Description: long chain-fatty acid beta-hydroxylating cytochrome P450, H(2)O(2)-dependent, hydroxylates myristic acid to beta-hydroxymyristic acid

Gene name cypC
Synonyms ybdT
Essential no
Product fatty acid beta-hydroxylating cytochrome P450
Function biosynthesis of beta-hydroxy fatty acid for lipopeptides
Gene expression levels in SubtiExpress: cypC
MW, pI 47 kDa, 6.468
Gene length, protein length 1251 bp, 417 aa
Immediate neighbours ybxI, ybyB
Sequences Protein DNA Advanced_DNA
Genetic context
CypC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CypC expression.png















Categories containing this gene/protein

general stress proteins (controlled by SigB), electron transport/ other, lipid metabolism/ other

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU02100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hydroxylation of a long-chain fatty acid (e.g. myristic acid) at the alpha- and beta-positions using hydrogen peroxide as an oxidant PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: cypC (according to DBTBS)
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References