Difference between revisions of "Map"

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|style="background:#ABCDEF;" align="center"|'''Function''' || removal of N-terminal methionine from nascent proteins  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || removal of N-terminal methionine from nascent proteins  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU01380 map]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01380 map]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[adk]]'', ''[[ybzG]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[adk]]'', ''[[ybzG]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11914&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01380 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01380 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01380 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:map_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:map_context.gif]]

Revision as of 11:59, 13 May 2013

  • Description: methionine aminopeptidase

Gene name map
Synonyms mapA
Essential yes PubMed
Product methionine aminopeptidase
Function removal of N-terminal methionine from nascent proteins
Gene expression levels in SubtiExpress: map
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation), Protein secretion
MW, pI 27 kDa, 6.393
Gene length, protein length 744 bp, 248 aa
Immediate neighbours adk, ybzG
Sequences Protein DNA Advanced_DNA
Genetic context
Map context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Map expression.png




























Categories containing this gene/protein

translation, protein modification, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01380

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)
  • Protein family: peptidase M24A family (according to Swiss-Prot)
  • Paralogous protein(s): YflG

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2MAT (from Escherichia coli, 46% identity, 65% similarity) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information: strongly expressed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References