Difference between revisions of "BsrA"
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| − | * '''Description:''' 6S RNA<br/><br/> | + | * '''Description:''' 6S RNA, important for timing of [[sporulation]]<br/><br/> |
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* reduced growth rate [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed] | * reduced growth rate [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed] | ||
* delayed outgrowth from stationary phase {{PubMed|22102588}} | * delayed outgrowth from stationary phase {{PubMed|22102588}} | ||
| − | + | * altered timing of onset of [[sporulation]] (earlier [[sporulation]]) {{PubMed|23457253}} | |
=== Database entries === | === Database entries === | ||
| Line 93: | Line 93: | ||
=References= | =References= | ||
'''Additional publications:''' {{PubMed|22333917,21881410,22102588}} | '''Additional publications:''' {{PubMed|22333917,21881410,22102588}} | ||
| − | <pubmed>12177353 15811922</pubmed> | + | <pubmed>12177353 15811922 23457253 </pubmed> |
[[Category:small RNA]] | [[Category:small RNA]] | ||
Revision as of 17:49, 5 March 2013
- Description: 6S RNA, important for timing of sporulation
| Gene name | bsrA |
| Synonyms | |
| Essential | no |
| Product | 6S RNA |
| Function | antagonist of SigA |
| Interactions involving this RNA in SubtInteract: BsrA | |
| Gene length | 190 bp |
| Immediate neighbours | yrvM, aspS |
| Gene sequence (+200bp) | |
Genetic context 
| |
Contents
Categories containing this gene/protein
sigma factors and their control, ncRNA
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU_misc_RNA_41
Phenotypes of a mutant
- reduced growth rate PubMed
- delayed outgrowth from stationary phase PubMed
- altered timing of onset of sporulation (earlier sporulation) PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: no entry
- Structure:
Additional information
- Similar RNA: bsrB
Expression and regulation
- Operon: bsrA PubMed
- Regulation: expressed in vegetative cells PubMed
- Regulatory mechanism:
- Additional information: transcribed as 201 nt RNA, processed to mature 190 bp 6S RNA PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
Labs working on this gene/RNA
Kouji Nakamura, Tsukuba, University, Japan
Roland Hartmann, Philipps-Universität Marburg, Marburg, Germany, Homepage
Your additional remarks
References
Additional publications: PubMed
Amy T Cavanagh, Karen M Wassarman
6S-1 RNA function leads to a delay in sporulation in Bacillus subtilis.
J Bacteriol: 2013, 195(9);2079-86
[PubMed:23457253]
[WorldCat.org]
[DOI]
(I p)
Jeffrey E Barrick, Narasimhan Sudarsan, Zasha Weinberg, Walter L Ruzzo, Ronald R Breaker
6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter.
RNA: 2005, 11(5);774-84
[PubMed:15811922]
[WorldCat.org]
[DOI]
(P p)
Satoru Suzuma, Sayaka Asari, Keigo Bunai, Keiko Yoshino, Yoshinari Ando, Hiroshi Kakeshita, Masaya Fujita, Kouji Nakamura, Kunio Yamane
Identification and characterization of novel small RNAs in the aspS-yrvM intergenic region of the Bacillus subtilis genome.
Microbiology (Reading): 2002, 148(Pt 8);2591-2598
[PubMed:12177353]
[WorldCat.org]
[DOI]
(P p)
