Difference between revisions of "SigB"
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− | + | * '''Description:''' [[RNA polymerase]] [[sigma factor]] SigB <br/><br/> | |
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigB_522862_523650_1 sigB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigB_522862_523650_1 sigB] {{PubMed|22383849}} | ||
− | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
** ''[[rsbR]]'': [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | ** ''[[rsbR]]'': [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | ||
** ''[[rsbV]]:'' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ** ''[[rsbV]]:'' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
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==Identification of the SigB regulon== | ==Identification of the SigB regulon== | ||
<pubmed> 11544224, 11532142, 11717291, 10482513, 10220166,22174379 </pubmed> | <pubmed> 11544224, 11532142, 11717291, 10482513, 10220166,22174379 </pubmed> | ||
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==Other publications== | ==Other publications== | ||
'''Additional publications:''' {{PubMed|22511268,22210769}} | '''Additional publications:''' {{PubMed|22511268,22210769}} | ||
+ | <pubmed> 23407164</pubmed> | ||
<big>''Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB'' </big> | <big>''Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB'' </big> | ||
<big>'''Stochastic pulse regulation in bacterial stress response.''' </big> | <big>'''Stochastic pulse regulation in bacterial stress response.''' </big> |
Revision as of 11:17, 15 February 2013
- Description: RNA polymerase sigma factor SigB
Gene name | sigB |
Synonyms | rpoF |
Essential | no |
Product | RNA polymerase sigma factor SigB |
Function | general stress response |
Gene expression levels in SubtiExpress: sigB | |
Interactions involving this protein in SubtInteract: SigB | |
Metabolic function and regulation of this protein in SubtiPathways: Stress, Murein recycling | |
MW, pI | 29 kDa, 5.418 |
Gene length, protein length | 792 bp, 264 aa |
Immediate neighbours | rsbW, rsbX |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
The SigB regulon
The gene
Basic information
- Locus tag: BSU04730
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SigB subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P06574
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant: QB5344 (cat), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
Your additional remarks
References
Reviews
Control of SigB activity by protein-protein interactions
Identification of the SigB regulon
Other publications
Additional publications: PubMed
Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB Stochastic pulse regulation in bacterial stress response. Science. 2011 334:366-369. PubMed:21979936