Difference between revisions of "YmxH"
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[sporulation]] protein |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
| Line 41: | Line 41: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[SigE regulon]]}} | |
=The gene= | =The gene= | ||
| Line 50: | Line 50: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * a ''[[ylmC]] [[ymxH]]'' double mutant has a severe [[sporulation]] defect (1% [[sporulation]] as compared to the wild type or single mutants), the block is at stage III of [[sporulation]] {{PubMed|23396918}} | ||
=== Database entries === | === Database entries === | ||
| Line 58: | Line 59: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| Line 106: | Line 106: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ymxH_1743924_1744181_1 ymxH] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ymxH_1743924_1744181_1 ymxH] {{PubMed|22383849}} | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|22383849,14523133}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed | + | ** expressed early during [[sporulation]] in the mother cell ([[SigE]]) {{PubMed|22383849,14523133}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 134: | Line 134: | ||
=References= | =References= | ||
| − | <pubmed>8098035 23123912 22383849</pubmed> | + | <pubmed>8098035 23123912 22383849 14523133 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:46, 13 February 2013
- Description: sporulation protein
| Gene name | ymxH |
| Synonyms | |
| Essential | no |
| Product | sporulation protein |
| Function | unknown |
| Gene expression levels in SubtiExpress: ymxH | |
| MW, pI | 9 kDa, 5.437 |
| Gene length, protein length | 255 bp, 85 aa |
| Immediate neighbours | mlpA, spoVFA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16720
Phenotypes of a mutant
- a ylmC ymxH double mutant has a severe sporulation defect (1% sporulation as compared to the wild type or single mutants), the block is at stage III of sporulation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YlmC
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q04811
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ymxH PubMed
- Regulation:
- expressed early during sporulation in the mother cell (SigE) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Bjorn A Traag, Antonia Pugliese, Jonathan A Eisen, Richard Losick
Gene conservation among endospore-forming bacteria reveals additional sporulation genes in Bacillus subtilis.
J Bacteriol: 2013, 195(2);253-60
[PubMed:23123912]
[WorldCat.org]
[DOI]
(I p)
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133]
[WorldCat.org]
[DOI]
(P p)
N Y Chen, S Q Jiang, D A Klein, H Paulus
Organization and nucleotide sequence of the Bacillus subtilis diaminopimelate operon, a cluster of genes encoding the first three enzymes of diaminopimelate synthesis and dipicolinate synthase.
J Biol Chem: 1993, 268(13);9448-65
[PubMed:8098035]
[WorldCat.org]
(P p)
