Difference between revisions of "TxpA"
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yqdB_2678240_2678419_1 txpA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yqdB_2678240_2678419_1 txpA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16166525 PubMed] | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16166525 PubMed] |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 143: | Line 143: | ||
==Original publications== | ==Original publications== | ||
| − | ''' | + | <big>''Durand S, Gilet L, Condon C'' </big> |
| + | <big>'''The essential function of ''B. subtilis'' RNase III is to silence foreign toxin genes.''' </big> | ||
| + | <big>PLoS Genet. 2012 8(12): e1003181.</big> | ||
| + | [http://www.ncbi.nlm.nih.gov/pubmed/23300471 PubMed:23300471] | ||
<pubmed>16166525, 19210617 </pubmed> | <pubmed>16166525, 19210617 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:40, 5 February 2013
- Description: toxic peptide
| Gene name | txpA |
| Synonyms | yqcR, yqdB |
| Essential | no |
| Product | toxic peptide |
| Function | toxin |
| Gene expression levels in SubtiExpress: txpA | |
| MW, pI | 6 kDa, 8.139 |
| Gene length, protein length | 177 bp, 59 aa |
| Immediate neighbours | yqbN/2, ratA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins, Skin element, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU26050
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane
Database entries
- Structure:
- UniProt: P54373
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: txpA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard University, Cambridge, USA Homepage
Your additional remarks
References
Reviews
Fabian M Commichau, Jörg Stülke
A mystery unraveled: essentiality of RNase III in Bacillus subtilis is caused by resident prophages.
PLoS Genet: 2012, 8(12);e1003199
[PubMed:23300472]
[WorldCat.org]
[DOI]
(I p)
Original publications
Durand S, Gilet L, Condon C The essential function of B. subtilis RNase III is to silence foreign toxin genes. PLoS Genet. 2012 8(12): e1003181. PubMed:23300471
