SigY

• Description: RNA polymerase ECF-type sigma factor SigY
  
  

Gene name	sigY
Synonyms	yxlB
Essential	no
Product	RNA polymerase ECF-type sigma factor SigY
Function	maintenance of the SPß prophage
Gene expression levels in SubtiExpress: sigY
Interactions involving this protein in SubtInteract: SigY
MW, pI	21 kDa, 9.549
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	yxlC, yxlA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription, sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigY regulon

The gene

Basic information

• Locus tag: BSU38700

Phenotypes of a mutant

• loss of the SPß prophage PubMed
• sensitive to killing by sublancin PubMed
• no production of sublancin PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ECF subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SigY-(RpoB-RpoC)
  • SigY- YxlC PubMed

• Localization:

Database entries

• Structure:

• UniProt: P94370

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sigY-yxlC-yxlD-yxlE-yxlF-yxlG PubMed

• Expression browser: sigY PubMed

• Sigma factor: SigY PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A909 ( sigY::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

The SigY regulon

Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383] [WorldCat.org] [DOI] (P p)

Other original publications

Additional publications: PubMed