Difference between revisions of "CheC"
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| − | * '''Description:''' [[CheY]]-P phosphatase, inhibition of [[CheR]]-mediated methylation of MCPs <br/><br/> | + | * '''Description:''' control of chemotaxis by interacting with [[CheD]], [[CheY]]-P phosphatase, inhibition of [[CheR]]-mediated methylation of MCPs <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 68: | Line 68: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' [[CheY]] phosphatase | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** [[CheY]]-P phosphatase | ||
| + | ** controls binding of [[CheD]] to chemoreceptors in response to the levels of [[CheY]]-P {{PubMed|23226535}} | ||
* '''Protein family:''' cheC family (according to Swiss-Prot) | * '''Protein family:''' cheC family (according to Swiss-Prot) | ||
| Line 89: | Line 91: | ||
** [[McpB]]-[[CheC]] {{PubMed|11722727}} | ** [[McpB]]-[[CheC]] {{PubMed|11722727}} | ||
** [[CheA]]-[[CheC]] {{PubMed|11722727}} | ** [[CheA]]-[[CheC]] {{PubMed|11722727}} | ||
| − | ** [[CheC]]-[[CheD]] {{PubMed|17908686}} | + | ** [[CheC]]-[[CheD]] {{PubMed|17908686}}, this interaction is enhanced by [[CheY]]-P {{PubMed|23226535}} |
** [[CheC]]-[[CheY]]-P | ** [[CheC]]-[[CheY]]-P | ||
| Line 148: | Line 150: | ||
=References= | =References= | ||
| − | <pubmed>7893679,14993307,18774298,8866475,18990184,17908686,14749334,11722727,9194713, 14651647, 9657996,8157612, 15175317,17609139, 16469702, 20080618,17675386,20133180 17850253 21515776</pubmed> | + | <pubmed>7893679,14993307,18774298,8866475,18990184,17908686,14749334,11722727,9194713, 14651647, 9657996,8157612, 15175317,17609139, 16469702, 20080618,17675386,20133180 17850253 21515776 23226535 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:53, 3 January 2013
- Description: control of chemotaxis by interacting with CheD, CheY-P phosphatase, inhibition of CheR-mediated methylation of MCPs
| Gene name | cheC |
| Synonyms | ylxJ |
| Essential | no |
| Product | CheY-P phosphatase |
| Function | motility and chemotaxis |
| Gene expression levels in SubtiExpress: cheC | |
| Interactions involving this protein in SubtInteract: CheC | |
| MW, pI | 22 kDa, 4.035 |
| Gene length, protein length | 627 bp, 209 aa |
| Immediate neighbours | cheW, cheD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
protein modification, motility and chemotaxis
This gene is a member of the following regulons
CodY regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16450
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: cheC family (according to Swiss-Prot)
- Paralogous protein(s):FliY
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: interaction with CheD enhances phosphatase activity towards CheY-P PubMed
Database entries
- Structure:
- UniProt: P40403
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
- in minimal medium, CheC is present with 770 +/- 330 molecules per cell PubMed
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
