Difference between revisions of "DapI"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[cell wall synthesis]]}}, | ||
| + | {{SubtiWiki category|[[biosynthesis of cell wall components]]}}, | ||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
{{SubtiWiki category|[[essential genes]]}} | {{SubtiWiki category|[[essential genes]]}} | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
Revision as of 16:02, 28 August 2012
- Description: N-acetyl-diaminopimelate deacetylase
| Gene name | ykuR |
| Synonyms | dapL |
| Essential | yes PubMed |
| Product | N-acetyl-diaminopimelate deacetylase |
| Function | biosynthesis of lysine and peptidoglycan |
| Gene expression levels in SubtiExpress: ykuR | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 41 kDa, 5.102 |
| Gene length, protein length | 1122 bp, 374 aa |
| Immediate neighbours | ykuQ, ykuS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, biosynthesis/ acquisition of amino acids, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14190
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: N-acetyl-LL-2,6-diaminoheptanedioate + H2O = acetate + LL-2,6-diaminoheptanedioate (according to Swiss-Prot)
- Protein family: peptidase M20A family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34916
- KEGG entry: [2]
- E.C. number: 3.5.1.47
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
The gene is annotated in KEGG as an ortholog of N-acetyldiaminopimelate deacetylase EC 3.5.1.47. In MetaCyc it is marked as “similar to hippurate hydrolase”. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is available. PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
