PbpC

• Description: penicillin-binding protein 3
  
  

Gene name	pbpC
Synonyms	ycsM, yzsA
Essential	no
Product	penicillin-binding protein 3
Function	unknown
Gene expression levels in SubtiExpress: pbpC
Interactions involving this protein in SubtInteract: PbpC
MW, pI	74 kDa, 6.202
Gene length, protein length	2004 bp, 668 aa
Immediate neighbours	yczJ, ycsN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis

The gene

Basic information

• Locus tag: BSU04140

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: transpeptidase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • may be part of the cell wall biosynthetic complex PubMed
  • folding requires PrsA PubMed

• Localization: cell membrane (according to Swiss-Prot), extracellular (signal peptide) PubMed

Database entries

• Structure:

• UniProt: P42971

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: pbpC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab

• Antibody: