QoxA

• Description: cytochrome aa3 quinol oxidase (subunit II)
  
  

Gene name	qoxA
Synonyms	ipa-37d
Essential	no
Product	cytochrome aa3 quinol oxidase (subunit II)
Function	respiration
Gene expression levels in SubtiExpress: qoxA
MW, pI	36 kDa, 4.796
Gene length, protein length	963 bp, 321 aa
Immediate neighbours	qoxB, ywzA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU38170

Phenotypes of a mutant

• inactivation of qoxA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membranePubMed

Database entries

• Structure:

• UniProt: P34957

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: qoxA-qoxB-qoxC-qoxD PubMed

• Expression browser: qoxA PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed