Difference between revisions of "NdoAI"
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| − | + | * '''Description:''' antitoxin, inhibits [[NdoA|EndoA]] <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || inhibition of [[NdoA]] | |style="background:#ABCDEF;" align="center"|'''Function''' || inhibition of [[NdoA]] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NdoAI NdoAI] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NdoAI NdoAI] | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:ydcD_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ydcD_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' ''[[ndoAI]]-[[ndoA]]'' {{PubMed|15882409}} | * '''Operon:''' ''[[ndoAI]]-[[ndoA]]'' {{PubMed|15882409}} | ||
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* '''Sigma factor:''' | * '''Sigma factor:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 11:29, 7 August 2012
- Description: antitoxin, inhibits EndoA
| Gene name | ndoAI |
| Synonyms | ydcD |
| Essential | no |
| Product | antitoxin |
| Function | inhibition of NdoA |
| Interactions involving this protein in SubtInteract: NdoAI | |
| MW, pI | 10 kDa, 6.138 |
| Gene length, protein length | 279 bp, 93 aa |
| Immediate neighbours | alr, ndoA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04650
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: mazE/ndoAI family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96621
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361]
[WorldCat.org]
[DOI]
(P p)
Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409]
[WorldCat.org]
[DOI]
(P p)
