Difference between revisions of "MrnC"
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| − | + | * '''Description:''' [[RNase]] Mini-III <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of 23S rRNA | |style="background:#ABCDEF;" align="center"|'''Function''' || maturation of 23S rRNA | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging]''' | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:yazC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yazC_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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* '''Operon:''' ''[[gltX]]-[[cysE]]-[[cysS]]-[[mrnC]]-[[yacO]]-[[yacP]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7510287 PubMed] | * '''Operon:''' ''[[gltX]]-[[cysE]]-[[cysS]]-[[mrnC]]-[[yacO]]-[[yacP]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7510287 PubMed] | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/7510287 PubMed] |
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* '''Regulation:''' repression by cysteine ([[T-box]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7510287 PubMed] | * '''Regulation:''' repression by cysteine ([[T-box]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7510287 PubMed] | ||
Revision as of 10:17, 7 August 2012
- Description: RNase Mini-III
| Gene name | mrnC |
| Synonyms | yazC |
| Essential | no |
| Product | RNase Mini-III |
| Function | maturation of 23S rRNA |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging | |
| MW, pI | 16 kDa, 9.153 |
| Gene length, protein length | 429 bp, 143 aa |
| Immediate neighbours | cysS, yacO |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00950
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: RNase III family (but lacks the dsRNA-binding domain)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed
Database entries
- Structure:
- UniProt: O31418
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism: T-box, overlaps a transcription terminator upstream of cysE: transcription antitermination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Ciaran Condon, IBPC, Paris, France Homepage
David Bechhofer, Mount Sinai School, New York, USA Homepage
Your additional remarks
References
