Difference between revisions of "KsgA"

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* '''Description:''' rRNA adenine dimethyltransferase <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || rRNA maturation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || rRNA maturation
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00420 ksgA]
 
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.712   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.712   
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|colspan="2" | '''Genetic context''' <br/> [[Image:ksgA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ksgA_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ksgA_50640_51518_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ksgA_expression.png|500px]]
 
 
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* '''Operon:''' ''[[rnmV]]-[[ksgA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11233981 PubMed]  
 
* '''Operon:''' ''[[rnmV]]-[[ksgA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11233981 PubMed]  
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ksgA_50640_51518_1 ksgA] {{PubMed|22383849}}
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* '''[[Sigma factor]]:''' [[SigF]] {{PubMed|16497325}}
 
 
* '''Sigma factor:''' [[SigF]] {{PubMed|16497325}}
 
  
 
* '''Regulation:''' expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325}}
 
* '''Regulation:''' expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325}}

Revision as of 10:12, 7 August 2012

  • Description: rRNA adenine dimethyltransferase

Gene name ksgA
Synonyms
Essential no
Product rRNA adenine dimethyltransferase
Function rRNA maturation
MW, pI 32 kDa, 5.712
Gene length, protein length 876 bp, 292 aa
Immediate neighbours rnmV, yabG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KsgA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation, sporulation proteins

This gene is a member of the following regulons

SigF regulon

The gene

Basic information

  • Locus tag: BSU00420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: methylation of A1518 and A1519 in 16S rRNA
  • Protein family: KsgA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed early during sporulation in the forespore (SigF) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References