Difference between revisions of "LigA"

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* '''Description:''' DNA ligase (NAD-dependent) <br/><br/>
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || replication  
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU06620 ligA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 74 kDa, 4.708   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 74 kDa, 4.708   

Revision as of 15:42, 6 August 2012


Gene name ligA
Synonyms lig, yerG
Essential yes PubMed
Product DNA ligase (NAD-dependent)
Function replication
Gene expression levels in SubtiExpress: ligA
MW, pI 74 kDa, 4.708
Gene length, protein length 2004 bp, 668 aa
Immediate neighbours pcrA, yerH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LigA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LigA expression.png
























Categories containing this gene/protein

DNA replication, essential genes

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

  • Locus tag: BSU06620

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: NAD+ + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + nicotinamide nucleotide + (deoxyribonucleotide)(n+m) (according to Swiss-Prot)
  • Protein family: BRCT domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1B04 (adenylation domain, Geobacillus stearothermophilus)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References