Difference between revisions of "SsrA"
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
* impaired growth at high and low temperatures {{PubMed|15805528}} | * impaired growth at high and low temperatures {{PubMed|15805528}} | ||
| + | * inactivation of ''[[ssrA]]'' restores beta-lactam resistance in a ''[[sigM]]'' mutant {{PubMed|22211522}} | ||
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=== Database entries === | === Database entries === | ||
| Line 104: | Line 106: | ||
==Original Publications== | ==Original Publications== | ||
| + | '''Additional publications:''' {{PubMed|22211522}} | ||
<pubmed>18977770,11395451,17369301,15805528,10881189,14766921, </pubmed> | <pubmed>18977770,11395451,17369301,15805528,10881189,14766921, </pubmed> | ||
[[Category:small RNA]] | [[Category:small RNA]] | ||
Revision as of 19:17, 21 July 2012
- Description: tmRNA
| Gene name | ssrA |
| Synonyms | |
| Essential | no |
| Product | tmRNA |
| Function | trans-translation |
| Gene length | bp |
| Immediate neighbours | yvaG, smpB |
| Gene sequence (+200bp) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
- impaired growth at high and low temperatures PubMed
- inactivation of ssrA restores beta-lactam resistance in a sigM mutant PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
- Structure:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant: GP323 (cat), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/RNA
- Chet Price, Davis, USA homepage
Your additional remarks
References
Reviews
Additional reviews: PubMed
Jeffrey H Withey, David I Friedman
A salvage pathway for protein structures: tmRNA and trans-translation.
Annu Rev Microbiol: 2003, 57;101-23
[PubMed:12730326]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Additional publications: PubMed
Hiromi Ujiie, Tomoko Matsutani, Hisashi Tomatsu, Ai Fujihara, Chisato Ushida, Yasuhiko Miwa, Yasutaro Fujita, Hyouta Himeno, Akira Muto
Trans-translation is involved in the CcpA-dependent tagging and degradation of TreP in Bacillus subtilis.
J Biochem: 2009, 145(1);59-66
[PubMed:18977770]
[WorldCat.org]
[DOI]
(I p)
Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J Bacteriol: 2007, 189(10);3729-37
[PubMed:17369301]
[WorldCat.org]
[DOI]
(P p)
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
Marc A B Kolkman, Eugenio Ferrari
The fate of extracellular proteins tagged by the SsrA system of Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 2);427-436
[PubMed:14766921]
[WorldCat.org]
[DOI]
(P p)
T Wiegert, W Schumann
SsrA-mediated tagging in Bacillus subtilis.
J Bacteriol: 2001, 183(13);3885-9
[PubMed:11395451]
[WorldCat.org]
[DOI]
(P p)
A W Karzai, E D Roche, R T Sauer
The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue.
Nat Struct Biol: 2000, 7(6);449-55
[PubMed:10881189]
[WorldCat.org]
[DOI]
(P p)
