Difference between revisions of "QoxA"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* inactivation of ''[[qoxA]]'' restores beta-lactam resistance in a ''[[sigM]]'' mutant {{PubMed|22211522}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 
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'''Additional publications:''' {{PubMed|22211522}}
 
<pubmed>11073895 1316894 20351111, 10551842,18763711, </pubmed>
 
<pubmed>11073895 1316894 20351111, 10551842,18763711, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:17, 21 July 2012

  • Description: cytochrome aa3 quinol oxidase (subunit II)

Gene name qoxA
Synonyms ipa-37d
Essential no
Product cytochrome aa3 quinol oxidase (subunit II)
Function respiration
MW, pI 36 kDa, 4.796
Gene length, protein length 963 bp, 321 aa
Immediate neighbours qoxB, ywzA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
QoxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
QoxA expression.png















Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU38170

Phenotypes of a mutant

  • inactivation of qoxA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O (according to Swiss-Prot)
  • Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed