Difference between revisions of "HisJ"
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<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hisJ_3031614_3032420_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:hisJ_expression.png|500px]] | ||
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Revision as of 11:07, 20 April 2012
- Description: histidinol phosphate phosphatase
Gene name | hisJ |
Synonyms | ytvP |
Essential | no |
Product | histidinol phosphate phosphatase |
Function | biosynthesis of histidine |
Metabolic function and regulation of this protein in SubtiPathways: His | |
MW, pI | 30 kDa, 5.061 |
Gene length, protein length | 804 bp, 268 aa |
Immediate neighbours | ezrA, yttP |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29620
Phenotypes of a mutant
auxotroph for histidine
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-histidinol phosphate + H2O = L-histidinol + phosphate (according to Swiss-Prot)
- Protein family: HisK subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34411
- KEGG entry: [2]
- E.C. number: 3.1.3.15
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Your additional remarks
References
D le Coq, S Fillinger, S Aymerich
Histidinol phosphate phosphatase, catalyzing the penultimate step of the histidine biosynthesis pathway, is encoded by ytvP (hisJ) in Bacillus subtilis.
J Bacteriol: 1999, 181(10);3277-80
[PubMed:10322033]
[WorldCat.org]
[DOI]
(P p)