Difference between revisions of "KamA"

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Revision as of 11:10, 19 April 2012

  • Description: lysine 2,3-aminomutase

Gene name kamA
Synonyms yodO
Essential no
Product lysine 2,3-aminomutase
Function unknown
MW, pI 53 kDa, 6.04
Gene length, protein length 1413 bp, 471 aa
Immediate neighbours yokU, yodP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KamA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
KamA expression.png

























Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon


The gene

Basic information

  • Locus tag: BSU19690

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-lysine = beta-lysine
  • Protein family: UPF0720 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: expressed early during sporuation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)