Difference between revisions of "CsrA"
Line 104: | Line 104: | ||
* '''Operon:''' ''csrA'' {{PubMed|8969505}} | * '''Operon:''' ''csrA'' {{PubMed|8969505}} | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=csrA_3636046_3636270_-1 csrA] {{PubMed|22383849}} |
+ | |||
+ | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
Line 110: | Line 112: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 07:34, 17 April 2012
- Description: motility regulator, binds to the hag mRNA to inhibit its translation
Gene name | csrA |
Synonyms | yviG |
Essential | no |
Product | motility regulator |
Function | control of hag translation |
Interactions involving this protein in SubtInteract: CsrA | |
MW, pI | 8 kDa, 6.09 |
Gene length, protein length | 222 bp, 74 aa |
Immediate neighbours | hag, fliW |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
RNA binding regulators, motility and chemotaxis
This gene is a member of the following regulons
The CsrA regulon: hag
The gene
Basic information
- Locus tag: BSU35370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: csrA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1T3O
- UniProt: P33911
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: csrA PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP469 (spc), available in Stülke lab
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Sampriti Mukherjee, Helen Yakhnin, Dave Kysela, Josh Sokoloski, Paul Babitzke, Daniel B Kearns
CsrA-FliW interaction governs flagellin homeostasis and a checkpoint on flagellar morphogenesis in Bacillus subtilis.
Mol Microbiol: 2011, 82(2);447-61
[PubMed:21895793]
[WorldCat.org]
[DOI]
(I p)
Helen Yakhnin, Pallavi Pandit, Tom J Petty, Carol S Baker, Tony Romeo, Paul Babitzke
CsrA of Bacillus subtilis regulates translation initiation of the gene encoding the flagellin protein (hag) by blocking ribosome binding.
Mol Microbiol: 2007, 64(6);1605-20
[PubMed:17555441]
[WorldCat.org]
[DOI]
(P p)
Prajna R Kulkarni, Xiaohui Cui, Joshua W Williams, Ann M Stevens, Rahul V Kulkarni
Prediction of CsrA-regulating small RNAs in bacteria and their experimental verification in Vibrio fischeri.
Nucleic Acids Res: 2006, 34(11);3361-9
[PubMed:16822857]
[WorldCat.org]
[DOI]
(I e)
B Soldo, V Lazarevic, C Mauël, D Karamata
Sequence of the 305 degrees-307 degrees region of the Bacillus subtilis chromosome.
Microbiology (Reading): 1996, 142 ( Pt 11);3079-88
[PubMed:8969505]
[WorldCat.org]
[DOI]
(P p)