Difference between revisions of "MenF"
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* '''Operon:''' ''[[menF]]-[[menD]]-[[ytxM]]-[[menB]]-[[menE]]-[[menC]]'' {{PubMed|9387221,1629163,8550504}} | * '''Operon:''' ''[[menF]]-[[menD]]-[[ytxM]]-[[menB]]-[[menE]]-[[menC]]'' {{PubMed|9387221,1629163,8550504}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=menF_3152302_3153717_-1 menF] {{PubMed|22383849}} |
| + | |||
| + | * '''Sigma factor:''' [[SigA]]: {{PubMed|8550504}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 16:00, 16 April 2012
- Description: menaquinone-specific isochorismate synthase
| Gene name | menF |
| Synonyms | icsM, entC |
| Essential | no |
| Product | menaquinone-specific isochorismate synthase |
| Function | biosynthesis of menaquinone |
| Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp, Menaquinone | |
| MW, pI | 52 kDa, 4.706 |
| Gene length, protein length | 1413 bp, 471 aa |
| Immediate neighbours | menD, yteA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30830
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Chorismate = isochorismate (according to Swiss-Prot)
- Protein family: isochorismate synthase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P23973
- KEGG entry: [3]
- E.C. number: 5.4.4.2
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504]
[WorldCat.org]
[DOI]
(P p)
J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163]
[WorldCat.org]
[DOI]
(P p)
