Difference between revisions of "FadB"
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** ''[[fadR]]-[[fadB]]-[[etfB]]-[[etfA]]'' {{PubMed|17189250}} | ** ''[[fadR]]-[[fadB]]-[[etfB]]-[[etfA]]'' {{PubMed|17189250}} | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fadB_2917166_2917942_-1 fadB] {{PubMed|22383849}} |
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+ | * '''Sigma factor:''' | ||
** ''[[fadR]]'': [[SigA]] {{PubMed|17189250}} | ** ''[[fadR]]'': [[SigA]] {{PubMed|17189250}} | ||
Revision as of 14:45, 16 April 2012
- Description: 3-hydroxyacyl-CoA dehydratase
Gene name | fadB |
Synonyms | ysiB |
Essential | no |
Product | 3-hydroxyacyl-CoA dehydratase |
Function | fatty acid degradation |
Metabolic function and regulation of this protein in SubtiPathways: Fatty acid degradation | |
MW, pI | 27 kDa, 4.951 |
Gene length, protein length | 774 bp, 258 aa |
Immediate neighbours | etfB, fadR |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O (according to Swiss-Prot)
- Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3PEA (from B. anthracis, 49% identity, 66% similarity)
- UniProt: P94549
- KEGG entry: [3]
- E.C. number: 4.2.1.17
Additional information
Expression and regulation
- Regulation:
- induced by long-chain fatty acids (FadR) PubMed
- subject to carbon catabolite repression (3.8-fold) (CcpA-HPr(Ser-P) PubMed
- Regulatory mechanism:
- FadR: transcription repression PubMed
- CcpA-HPr(Ser-P): transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed