Difference between revisions of "FeuA"
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* '''Operon:''' ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] | * '''Operon:''' ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=feuA_182370_183323_-1 feuA] {{PubMed|22383849}} |
+ | |||
+ | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] | ||
* '''Regulation:''' | * '''Regulation:''' |
Revision as of 12:57, 12 April 2012
- Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (binding protein), with YusV as ATPase
Gene name | feuA |
Synonyms | |
Essential | no |
Product | ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (binding protein) |
Function | acquisition of iron |
Interactions involving this protein in SubtInteract: FeuA | |
Metabolic function and regulation of this protein in SubtiPathways: Stress, Metal ion homeostasis | |
MW, pI | 34 kDa, 8.018 |
Gene length, protein length | 951 bp, 317 aa |
Immediate neighbours | feuB, btr |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
ABC transporters, acquisition of iron, iron metabolism, membrane proteins
This gene is a member of the following regulons
Btr regulon, CitB regulon, Fur regulon
The gene
Basic information
- Locus tag: BSU01630
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/biological activity:
Substrate binding protein for the triscatecholate siderophores ferri-bacillibactin and ferri-enterobactin and part of the FeuA-FeuB-FeuC-YusV ATP-binding cassette-type transporter. Furthermore ferric complexes of L-norepinephrine are bound by this protein.
- Protein family: Fe/B12 periplasmic-binding domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
Two independent non-symmetric globular domains, connected by a long alpha-helix (residues 143-164 of the mature protein).
- Modification:
- FeuA is a lipoprotein with a N-acetyl-S-diacyl-glyceryl-cysteine structure PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2PHZ, 2WI8, 2WHY (complex with ferri-bacillibactin), 2XUZ (complex with ferri-enterobactin), 2XV1 (complex with ferric mecam)
- UniProt: P40409
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed