Difference between revisions of "Easter egg"

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* '''Description:''' RNA component of [[RNase]] P <br/><br/>
 
  
{| align="right" border="1" cellpadding="2"
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|''rnpB''
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP ''
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme)
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Gene length''' ||  401 bp
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypsC]]'', ''[[ypsB]]''
 
|-
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/rnpB_nucleotide.txt    Gene sequence      (+200bp)  ]'''
 
  
|-
+
[[File:Example.jpg]]
|colspan="2" | '''Genetic context''' <br/> [[Image:rnpB_context.gif]]
 
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|}
 
 
 
__TOC__
 
 
 
<br/><br/><br/><br/><br/><br/><br/>
 
 
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[Rnases]]}},
 
{{SubtiWiki category|[[translation]]}},
 
{{SubtiWiki category|[[ncRNA]]}}
 
 
 
= This gene is a member of the following [[regulons]] =
 
 
 
 
 
=The gene=
 
 
 
=== Basic information ===
 
 
 
* '''Locus tag:'''
 
 
 
===Phenotypes of a mutant ===
 
 
 
=== Database entries ===
 
 
 
* '''DBTBS entry:''' no entry
 
 
 
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045]
 
 
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from Geobacillus stearothermophilus),  [http://www.rcsb.org/pdb/explore.do?structureId=1NBS 1NBS] (specificity domain)
 
 
 
 
 
 
 
=The RNA=
 
 
 
* '''Biological activity:''' 5' end maturation of precursor tRNAs
 
 
 
* '''RNA family:'''
 
 
 
* '''cofactor:''' divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA {{PubMed|20434461}}
 
 
 
* '''interaction:''' [[RnpA]]-RnpB
 
 
 
=== Additional information===
 
 
 
=Expression and regulation=
 
 
 
* '''Operon:'''
 
 
 
* '''Sigma factor:'''
 
 
 
* '''Regulation:'''
 
 
 
* '''Regulatory mechanism:'''
 
 
 
* '''Additional information:'''
 
 
 
=Biological materials =
 
 
 
* '''Mutant:'''
 
 
 
* '''Expression vector:'''
 
       
 
* '''lacZ fusion:'''
 
 
 
* '''GFP fusion:'''
 
 
 
* '''two-hybrid system:'''
 
 
 
* '''Antibody:'''
 
 
 
=Labs working on this gene/RNA=
 
* [[Carol Fierke]], University of Michigan, Ann Arbor, USA [https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=fierke homepage]
 
* [[Roland Hartmann]], Marburg University, Germany [http://www.pharmazie.uni-marburg.de/pharmchem/akhartmann/ag_hartmann.htm homepage]
 
 
 
=Your additional remarks=
 
 
 
=References=
 
==Reviews==
 
<pubmed> 19215776 17868095 14691942 16650980 16980936 16679018 14550630 </pubmed>
 
 
 
==Original Publications==
 
<pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747  19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>
 
 
 
[[Category:small RNA]]
 

Latest revision as of 16:46, 11 March 2012


Example.jpg