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− | * '''Description:''' RNA component of [[RNase]] P <br/><br/>
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− | {| align="right" border="1" cellpadding="2"
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− | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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− | |''rnpB''
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− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP ''
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− | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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− | |style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme)
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− | |style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs
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− | |style="background:#ABCDEF;" align="center"| '''Gene length''' || 401 bp
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− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypsC]]'', ''[[ypsB]]''
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− | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/rnpB_nucleotide.txt Gene sequence (+200bp) ]'''
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| + | [[File:Example.jpg]] |
− | |colspan="2" | '''Genetic context''' <br/> [[Image:rnpB_context.gif]]
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− | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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− | |}
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− | __TOC__
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− | <br/><br/><br/><br/><br/><br/><br/>
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− | = [[Categories]] containing this gene/protein =
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− | {{SubtiWiki category|[[Rnases]]}},
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− | {{SubtiWiki category|[[translation]]}},
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− | {{SubtiWiki category|[[ncRNA]]}}
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− | = This gene is a member of the following [[regulons]] =
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− | =The gene=
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− | === Basic information ===
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− | * '''Locus tag:'''
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− | ===Phenotypes of a mutant ===
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− | === Database entries ===
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− | * '''DBTBS entry:''' no entry
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− | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045]
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− | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=1NBS 1NBS] (specificity domain)
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− | =The RNA=
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− | * '''Biological activity:''' 5' end maturation of precursor tRNAs
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− | * '''RNA family:'''
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− | * '''cofactor:''' divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA {{PubMed|20434461}}
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− | * '''interaction:''' [[RnpA]]-RnpB
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− | === Additional information===
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− | =Expression and regulation=
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− | * '''Operon:'''
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− | * '''Sigma factor:'''
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− | * '''Regulation:'''
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− | * '''Regulatory mechanism:'''
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− | * '''Additional information:'''
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− | =Biological materials =
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− | * '''Mutant:'''
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− | * '''Expression vector:'''
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− |
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− | * '''lacZ fusion:'''
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− | * '''GFP fusion:'''
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− | * '''two-hybrid system:'''
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− | * '''Antibody:'''
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− | =Labs working on this gene/RNA=
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− | * [[Carol Fierke]], University of Michigan, Ann Arbor, USA [https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=fierke homepage]
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− | * [[Roland Hartmann]], Marburg University, Germany [http://www.pharmazie.uni-marburg.de/pharmchem/akhartmann/ag_hartmann.htm homepage]
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− | =Your additional remarks=
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− | =References=
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− | ==Reviews==
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− | <pubmed> 19215776 17868095 14691942 16650980 16980936 16679018 14550630 </pubmed>
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− | ==Original Publications==
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− | <pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747 19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>
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− | [[Category:small RNA]]
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